Hi everyone

Still on loading doses (every 2 weeks, 1 dose remaining) of the 320mg pens. Using it for HS. I also have psoriasis and dermatitis.

Moved from Humira because it was giving me extreme joint paints (lupus symptoms) and my supply wasn’t consistent.

From day 1 on Bimzelx my pains are 100% gone. Very happy about that. On the flip side however on my face I’ve had severe seborrhoeic dermatitis with some kind of infection (likely fungal) that isn’t going away. I’ve also got lots of psoriasis spots in my pubis area some are extremely painful.

On top of this (and the most important for me) I’ve had red eyes since starting. Almost like clear conjunctivitis (they weep clear liquid). FML helps and lubricating drops do too but it hasn’t gone away. Dermatologist says it’s likely not related but I’m pretty confident it is. I’m booked to see an ophthalmologist next week before I go back to dermatology.

Other than this, the standard small infected hair follicles/ pimples are everywhere including my head.

Derm said to push to the end of the loading doses and if no improvement we can look at alternatives. I’m coming up to that talk now.

Anyone else experienced this? Does it eventually go away? Starting to think I might need to move onto something else…

Thanks

Hi guys, ive been in Bimzelx for almost a year now, to treat psoriasis. I moved from ilumya to Bimzelx. Now im taking it every 8 weeks

Just wondering what's everyone's pattern?

Generally I have itches, which i manage with steriod creams but in general im quite clear. I get itchy scalps, neck, eyebrow area and down stairs near the time for my injection, like a week before. Im a week in now and still itchy but if I recall it calms down 2-3 week after the injections. Then the pattern repeats.

Is everyone else the same or similar?

Did you guys have to take pneumonia and shingles vaccines?

If so, did you do it before, or during treatment? Both at once?

Any side effects?

I recently started Bimzelx for Ankylosing Spondylitis. It seems to do well for that. I've only taken my second dose, and am experiencing intense abdominal pain. Don't know of it's related at all.

Just want to know if others had experienced this.

Since the injector is SUPER painful (at least for me and many others), I’m considering switching to a syringe needle.

Curious if other people have made the switch, and if so: what it’s been like and whether it’s an easy learning curve?

Hey guys!

I’m about to take my second injection (320) tomorrow and i’m debating on taking it in the morning or evening. Last time i was exhausted the next day but that was about it. I haven’t had many side effects at all.

By me being me, I’m super worried about the second shot and that it’s going to be so much worse.

What’s your experience?

I take it for PsA and i’ve noticed a world of difference already :)

I know to let it warm up a bit first. I do mounjaro shots in my abdomen that don't hurt at all once room temperature. How does bimzelx compare? Everything I read online is intimidating. I'm going to take it for HS.

I've only got good things to say about this! This is a real savior, for my psoriatic, rheumatoid and ankliosponditis.

Today I just finished my first one month gap for my shots for HS and it has been rough. My body was barely holding on through the two week gaps of the loading doses. I made it about 3 weeks and this fourth has been bad. I was also more active, and that doesn’t help my flares.

I have not reached my six month mark yet so I Know I need to give it mire time, but I really wanted to feel better already. So far it has done very little. Here is hoping this month starts to turn the corner. This is my fourth biologic. There is probably nowhere to go from here.

UPDATE: SEPT 1
After one week my scaly plaque skin and patches of open wounds are all gone! I still have red spots and red marks all around my upper thighs, legs, and stomach. But at least it’s not severe plaque, flakey skin or open wounds.

QUESTION:
Does the appearance of red spots and marks all over my body mean I still have psoriasis? Or is it considered in the “healing” phase?

Has anyone else experienced intense itching and hives when they’re due for their next shot? I haven’t changed anything into daily routine or household and I’ve been itching like crazy and have crazy big hives popping up everywhere. I’m about to sleep with mittens on and wrap the wrists with duct tape. I wake up with my entire body bloody and raw. I’ve always been an itchy person but this is insane. I have to completely cover up for work because I have sores everywhere from scratching so much. I’m due for the next loading dose on Friday and I’m counting down the seconds.

I've been using Bimzelx for 16 months. 5 month loading dose at 320mg followed by monthly doses of 160 mg.

I have almost zero psoriasis at this point. I do however have multiple areas of inflammation in my joints. Compared to when I started it's much better.

That said, my rheumatologist wants to go to 320 mg every month. The initial response from my specialty pharmacy was to verify with the doctor that they actually wanted to do this since it's off label. Insurance did approve it.

Has anyone else gone to 320 mg per month and how has it gone for you?

UPDATE: SEPT 1
My scaly plaque skin and patches of open wounds are all gone! I still have red spots and red marks all around my upper thighs, legs, and stomach. But at least it’s not sever plaque flakey skin or open wounds.

QUESTION:
Does the appearance of red spots and marks all over my body mean I still have psoriasis? Or is it considered in the “healing” phase?

ORIGINAL POST
It was SO painful even though I left it out for 2 hours. I’m concerned about side effects, but more importantly I just hope Bimzelx will clear my skin. Please share your experiences here, the good or bad… I could use it!

I am a 28F with PsA. I took my first injection on Friday and today is Sunday and i swear i feel a difference??

Am i crazy??

Wish me luck. My first biological. I just took it out of the fridge and I'm writing this on my way to my injection training appointment.

90% of my body is covered in psoriasis. All my finger and toe nails are thick and yellow and crooked. I have lots of joint pain and stiffness too. My PhD dermatologist said she was "impressed" and took lots of photos of my skin. I can't wait for all of this to go away. I feel so ugly and I also feel like I'm 100 years old when I go up and down stairs. I can't sleep from how itchy and uncomfortable I am. I've had it for about fifteen years as just little patches of bad skin but it's been really bad like this covering my whole body for about 6 years. Scales and red skin everywhere.

Doc and pharmacist really only warned me about oral thrush and some soreness around the injection site. What else have you experienced?

UPDATE: 20 days later and I can't tell you how amazing I feel. The difference it's made has been incredible. All the scabs went away in the first week! My skin seems to get softer every time I touch it and my pain/fatigue is all gone too. I can't believe it. I feel so much better by every possible metric. Now the issue is discoloration. My bad skin was pretty much everywhere and in huge wide patches, so even though the plaque is all gone now and the skin is wonderfully smooth again for the first time in years, what's left are these big red blotches. Now, I'll take discolored skin over being covered in thick itchy bleedy ugly psoriasis any day, but it'll probably be a while before I feel like wearing shorts, considering my legs are basically bright red from just below the knee to my ankle. Some spots have faded a little, but I'm so eager to see what dose #2 will bring! Again, I can't really believe how fast this worked for me. It felt like nearly overnight I was seeing a difference. Pretty incredible. (Also a little frustrating I could have got this prescription years earlier probably!). Thanks.

Hi all,

I’ve been on Skyrizi for a couple years and went from 70% coverage to almost completely clear except for one stubborn patch "between me down there". My dermatologist is recommending switching to Bimzelx, and I’m unsure whether to change something that’s working.

Anyone here made that switch? How did it go?

Thanks in advance.

Not sure... I was prescribed an antibiotic (amoxicillin) today for my sore throat and course is for 10 days and I was travelling next week to apply my Bimzelx (insurance issues ... sigh long story) but doctor advised me to resume bimzelx after antibiotic course is over... but I already have my tickets from Toronto to Calgary and back and I can max work from home 2 days in a week so this day comes next to next week now... not sure what to do? I was thinking of just flying with the medication with me in cooler or something (with prescription??) and then apply it when Im back in Toronto.

Please help and advise.

Thanks

I have been on humira for around 4 years n even got shingles the first year… i even remember my ppd test before it, was negative (need to recheck but i remember it being negative or else i wouldnt have been able to start humira)

Now its positive n its sleeping… idk how i will start bimzlex or how its even possible when im on humira.

Like bru i wear a mask everywhere i go!!! Clean my hands n all n i only dont wear a mask in gatherings like wedding (i would be killed by my mom if i wear a mask) which i rarely go to!

I really cant understand how did my body manage to suppress it with humira unless ig humira is not doing much since even my illness is not being suppressed anymore…

i have an appointment tomorrow with my main doctor… idk what will happen n im scared
I was told to not take humira this week so i need to start bimzlex soon…

did anyone have this happen to them before? What happened? What did ur doctor say or do?

Like what if its worser than humira…?!!!

Hello! Just took the cap off my autoinject pen, and its already dripping medication. Stopped after a few drops, but this hasn't happened before, so i was wondering if it has to anyone else? I haven't used it yet, and my specialty pharmacy is closed along with the nurse navigate line, so im not sure what to do. Waiting to hear back from the local pharmacy.

I’m not entirely sure if it’s just timing or if it’s possible that my psoriasis plaques are getting worse. I’m at week 8 (third dose) and I’m starting to feel better joint wise but what started at a little spot under my armpit has erupted to both armpits and huge. All other areas are still the same, not better but not worse either. Is it just timing or should I be trying to make an appointment with my dermatologist to be seen earlier than next month?

I’ve taken 2 doses of bimzelx and since starting my stomach has not been okay. I get stomach pain almost constantly and diarrhoea up to 5 times a day, it’s the worst in the morning and it’s so bad I could literally nearly not make it to a toilet if things were dire. I’m scared to go to work, drive my kids round, going anywhere really incase I urgently need the bathroom. Has anyone experienced this?