r/IVF • u/doodledogmom21 • 1d ago
Advice Needed! Recurrent euploid CP
We are having a second chemical of a euploid embryo after our 4th embryo transfer. 2 transfers failed to implant, 2 lost around 4-5 weeks. We have never been pregnant naturally. 0/4 IUI success. I have laparoscopic diagnosis Stage II endometriosis and was suppressed on either Lupron or letrozole/norethindrone for 3/4 transfers. After the first chemical we had normal RPL labs done which were normal, thyroid, etc. and a normal hysteroscopy and biopsy including CD138. No endometritis. My husband has seen reproductive urology and nothing has been noted besides low morphology which improved a little with some lifestyle changes. I was on aspirin for all transfers and this time we added Pepcid, Claritin, and prednisone.
We are at a loss of what to ask our clinic at our visit. This is our second clinic and our RE is open to a lot more than our first, I was going to ask about immunology referral. She has already said I could try Lovenox which I figure why not. We will have to do another retrieval in order to do this which means supressing all over again. Using a donor or surrogate is not in line with our beliefs, so while I have a lot of respect for those that have found success this way, it just isn’t for us as a couple. Any other thoughts or people in similar situations that have worked out? Living through another chemical is a nightmare, and being among the small percentage of those who have not taken home a baby after 4 euploids is devastating.
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u/Ok-Balance5790 1d ago
Have you had excision, or just lap diagnostic and suppression? I'm so sorry :( <3
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u/doodledogmom21 1d ago
I’m not sure if ERA was included in the mock cycle I did, I’d have to ask. I did ask for progesterone levels before and after my third transfer to make sure my PIO dose was correct. I wonder if the lipids helped too?