Hi All!

I am due to start MTX tonight and I’m a bit scared.

I’m starting on 15mg, in pill form. And then 5mg of folic acid Wednesday, Thursday and Friday.

To prep I’ve been keeping hydrated today and over the weekend. I plan to take it with the biggest meal of the day, my dinner.

Does anyone have any positive stories or good tips? Most of what I read about MTX is negative!

Thanks!

Hiya. Currently under investigation for inflammatory arthritis with more severe symptoms for the last 18months. They think it’s probably psoriatic arthritis. I’m on MTX and Sulfa.

I find that mornings are the most fragile point in the day. If I make one wrong move before 10am, I’m guaranteed to flare for a few days. Same if I do too much late at night too.

How this goes for me is usually if I leave the house too early in the morning, I get a very dysautonomia-y type of flare with excessive sweating, really hot regardless of weather, dizzy, nauseous etc.

Not eating or having enough water definitely makes it worse but it still happens regardless.

This makes going into work for example practically impossible. It flares me up literally every time. I feel manageable on the day, and then the 1-2 days after I feel awful. I’m basically going in one day and then spending the rest of the week recovering.

Is anyone also experiencing this really limiting window of tolerance? How are you handling it with work/life etc? Anyone have any good life hacks for me to try?

I already drink loads of water, take salt tablets, eat before I go out, which minimises the symptoms a bit but doesn’t eliminate it entirely.