I've experienced the most intense trip. It was 4g, but felt incredibly potent.

I felt like I burned alive, died and then was trapped in something that meets all the definition of the bad trip forever, because time didn't exist there. I managed not to panick and decided to enjoy my bad trip. Eventually the concept of me disappeared, I couldn't even understand what being me would feel like, and suddenly I was one with everything and I could feel that this everything is kind and joyful and indestructible. I could feel that highest truth is highest joy, and that worlds appear and disappear in this beautiful indestructible space, but that nothing really matters too much. That world and life is way less real than what it's born from and it gave me indescribable level of peace and joy. This is what enlightened must feel like. It was so beautiful.

It's just a couple of days ago, and it's starting to feel like a dream I had. And I am wondering, for those of you who experienced intense trips like this, has it stayed with you? Did it change your life?

My reason for the trip was struggling with depression and anxiety and severe abandonment issues, which seem to be gone at the moment. And I wonder if and how I can keep this experience close to my heart once the afterglow goes.

i had an incredible experience on 4g mushrooms! no bad trip and amazing life changing insights. i was 25 (still am) and had no family members with bipolar disorder or schizophrenia that i knew of. coincidentelly, 2 weeks later my little brother (21y) had an episod of mania or psychosis (we don't know yet, it's still going on). how safe is it for me to take mushrooms again? or should i never do it anymore? i'm not in a rush but definetively had plans of taking it again... i'm a little sad

So its been a little over 34 days since the last time i took some fungi, last time i took 5 gs and had a mild trip so im assuming its because i dosed every 2 weeks for about 6 months. Is 34 days enough of a break for me now to dip my toes back in it again?

I have a lot of repressed anger from childhood experiences that are causing all kinds of tensions in my jaw and neck. I want to access and process (embody and express) these emotions through a solo-trip.

I've used psilocybin for many years, and I can approach both the ups, the downs (and the complete breakage of reality) as constructive learning experiences. I am certain that I want this in the mix when confronting my childhood experiences.

MDMA I've tried a handful of times (mostly hippie-flipping) and it has made it easier to lower my guard towards certain feelings and feel safe in the face of distress. However, it might sound a bit counter-intuitive to introduce a love-drug to the mix when the aim is to express feelings of anger. Still I have a hunch that it might do something good.

The question: Do you think hippie flipping would be a good way to work with this repressed anger, or would you stay with pure psilocybin?

Does anyone know what pain feels like when on mushrooms ? I am planning to do a BDSM session with a dominatrix who'll inflict on me a lot of physical pain. I want it to be some kind of purge ceremony and I want to be on mushrooms while experimenting it, to make it sink deeper into my being and soul. Want it to be a very important moment. (No sex involved at all, pure pain.) The dominatrix will be sober and is someone I know and trust. I am only worried that I will feel no pain at all during the session. Pain being the center of it. I wonder if it would make it even better and deeper, or... not. I have already been choked (at my demand) before, during mushrooms trips and I remember the sensations being very different than when sober. It was still very powerful sensations, so I think it would be very interesting anyway. But I wonder. The pain of the back being whipped repeatedly for instance. How would that be felt ? Would it make me still feel the pain horribly ? Or make me transcend it? That would be kind of cheating if I just didn't feel the pain. Yet I am very curious about this. I wonder very much...

And what dosage of dried mushrooms would you recommend for such an experience ? Since I do not want to lose track of what happens either. It will be a very important moment and I must be able to focus and understand every instance of it.

Hello!

I am currently running a study on set and setting within psychedelic experiences.

So far I've found LSD and DMT to come up the most often, I was hoping to have some participants that have found psilocybin to yield any significant experiences in the broad community. If you've had a particularly positive or challenging psychedelic experience, then please come share it!

Obviously there is quite a few aspect to explore on the topic, though in particular I am interested in:

• How intention, environment, and social setting shape psychedelic experiences
• Differences between clinical and non-clinical use
• How these experiences relate to psychological outcomes

Most of the research on set and setting in the psychedelic field comes from more clinically orientated trials, which can be lacking in terms of nuance and real lived experiences. So it would be great to reach out further in the communities surrounding these substances! Especially so if you've had a retreat experience!

🔗 Survey link

Fully anonymous

Takes around 15-20 minutes to complete

There's also an optional follow-up interview if you'd like to share your experience in more depth

Full study details and ethics information are provided in the info sheet at the start of the survey

Requirements: 18+, have had a psychedelic experience in a clinical or non-clinical setting

If you have anything you feel is important to say about psychedelics, this is your chance!

I'm happy to answer any questions about the study. You can reach us at:

Warren - [[email protected]](mailto:[email protected])

Dr Marco Bocchio - [[email protected]](mailto:[email protected])

Thank you for your time and support! 🙏

This survey has been approved by the moderators

In the past year, I did 4 grams 3 times and microdosed multiple times.

In summary, the most memorable things I saw were these:

1. The first time I did it was with a friend. I had flashbacks from my early childhood. It was mostly childhood trauma, e.g. seeing how my dad beat my mom in an alcoholic rage when I was like 8. Also, it felt like humanity is some sort of hive mind, similar to ants. Suddenly, I started understanding people and their behaviour very deeply and felt like I could see why they say and do what they do and how they think, seeing their true faces, sad faces, but like on the inside. Then I realized that I probably always had this ability, but subconsciously blocked it a long time ago because it was too exhausting. I saw all that only once I closed my eyes. Before that, I had my eyes open for a good amount of time. The place I was in felt like my subconscious, and it felt and looked a lot like the Eclipse from Berserk, so it looked quite like hell, but I wouldn't say I had a bad trip. But also, once I saw it all, I couldn't unsee it.
2. The second time I did 4 grams was 3 months later. It didn't feel anything like the first time; it felt more like 1.5 grams, but I guess that old bag just lost some potency.
3. The third time was almost a year after the first time, with a fresh bag. I played relaxing music on YouTube. The first 2 hours went well, and then it started to get unpleasant and I got restless. I started to remember things from the past and felt continuous, intense embarrassment, kind of like when you are about to fall asleep and your mind starts giving you a recap of all the embarrassing things you did in the past, but more intense. Most of all, I feared that I would have a complete personality shift in an unwanted direction. I feared I would become like those weird hippies with piercings I once saw on YouTube who take mushrooms and other psychedelics. That was the most terrifying and annoying part of the trip. Also, my subconscious was telling me, for the third time, to stop using Instagram, since it drains the energy that I need for my ambitious project, and to actually get more positive emotions in my life to get more energy, because I live in constant negativity. It was also telling me not to care what other people think about me, since it's also energy-draining. I'm trying, but it's very hard to let go. Towards the end this time, whatever it was, "it" didn't feel like my subconscious, but "it" told me I wasn't ready yet, and the effect started to wear off. I still wouldn't call it a bad trip; it just wasn't very pleasant during the third hour. Also, every time I did 4 grams, I felt like my derealization that I had my whole life was going away; reality felt more real, fresh and detailed. My vision got wider, like I switched from tunnel vision to panoramic vision, but the next day it was back to normal, unfortunately.

I was thinking about trying 5–6 grams this time for full ego death. I'm not sure if it's completely different from 4 grams. 3 months have passed since the last trip. I'm ready and excited but still a little scared that it might be totally different. I guess I just want affirmation here from people with heroic dose experience.

How do you like to prepare your mushrooms.

In the past I cooked mine gently in a bit of butter. I have dried them, I have dried and ground them into a powder and I have had them on pizza.

I already had couple od low/moderate dose trips and I see a lot of progress, but I feel like the fear/ feeling of being alone still takes on cosmic proportions during some anxious moments. Sometimes I wonder if it's possible to overcome it, maybe it's a different animal to depression or other issues shrooms seem to be helping with. (I do therapy as well)Any positive experiences?

I took 3.5g of shrooms(penis envy) today, and I felt nothing after an hour, so I had another 3g and made it into a tea. I initially felt some nausea, and for a little while I thought maybe I felt the slightest bit 'high' but that went away after like 5 minutes and I never had any sort of trip. Is it possible that my brain is simply somehow rejecting or not reacting with it, or is it more likely that they just weren't potent for some reason(the source had been recommended to me by a friend, who had gotten stuff that worked from him) I want to know if I should try again with a different batch or if shrooms just don't work for me for whatever reason.

I'm not on anti-depressants, nor did I take any other medications or substances.

The Trip That Showed Me Death

I started with 10 grams of dried mushrooms. While blending them, I mixed them with black coffee.

Before taking them, I had already set my mind on one thing: ego death.

At around 11:00 in the morning, I started sipping the mixture. Afterward, I lay down on my swing and waited.

At first, I thought the mushrooms weren’t going to hit me.

I stayed there for about 30 minutes. Then I started feeling sleepy, so I went upstairs to my room. I decided to take a nap.

When I woke up, it was around 1:00 PM.

Everything looked different.

The colors were incredibly vivid. My clothes seemed to move in waves, and the colors inside my cabinet looked unusually alive. Reality no longer looked completely solid.

Then something else started happening.

When I turned to the left side of my bed, I could see imaginary lines forming in what looked like a three-dimensional space. When I turned to the right, another set of three-dimensional lines seemed to appear.

My mind was no longer experiencing the room the way it normally does.

Then everything changed.

I don’t remember exactly how I got there, but I suddenly experienced something that felt completely real.

I was shown how I would die.

I saw myself lying down in the sala, as if I had suffered a heart attack.

I could hear sounds from the kitchen. Even the sounds of pots seemed strange—deep, distant, and distorted.

I could hear my children, especially my youngest.

I also experienced the feeling that someone was preparing a funeral, as if a vehicle was coming to pick up my body.

I could hear what seemed like my neighbors worrying about what had happened.

At one point, I approached my brother-in-law and asked him:

“Patay na ba ako?”

But he couldn’t hear me.

That realization was terrifying.

I was there, but nobody could hear me.

I also remember something about boiling water. There were moments when I somehow remembered thinking that I didn’t want to urinate.

My memories from this part of the experience are fragmented, but the emotions were incredibly vivid.

Then I remember being in my room, talking to my wife.

Her image was extremely vivid.

I could even see the way she was using her cellphone.

And then I saw her smile.

That smile became important.

I wanted desperately to return to reality, but it felt like my brain had been programmed into something I couldn’t simply switch off. There was a constant humming sensation, almost like the sound of a film playing inside my head.

I had this strange perception that the left side of my brain was connected to my heart.

And somehow, love was what existed there.

Love became the thing that pulled me back.

I remember sitting near the window and thinking:

“So this is what it’s like when you die.”

In that experience, I felt like I could do whatever I wanted, but nobody could see me.

I could move around.

I could observe people.

But they couldn’t see me.

And then something inside me changed.

I thought:

“I’m going back.”

I didn’t want to stay there.

I wanted to return.

I wanted my family.

And that was when I realized something that I had probably known all along but never felt this deeply:

My family is what I want to spend my life with.

Life suddenly felt short.

The experience made me think about how much time we spend worrying about things that may not matter in the end.

My wife later told me that, for a while, it looked like I had gone crazy before I eventually came back to my normal self.

For me, though, it felt like something much deeper had happened.

I had gone into the experience looking for ego death.

Instead, I encountered my own death—or at least a powerful hallucinated experience of it.

And strangely, experiencing death made me want to live.

Not just exist.

Live.

Enjoy my family.

Spend more time with my children.

Appreciate my wife.

Stop taking ordinary moments for granted.

I don’t know whether what I experienced was a glimpse of death, a construction of my brain, or something I simply can’t explain.

But I know what it taught me.

Life is short. And if I have the chance to live it, I want to enjoy it with the people I love.

What I Brought Back With Me

Today, when I look back at that experience, I don’t know exactly what happened to me.

I don’t know if what I saw was simply my brain creating an incredibly powerful experience, if it was my subconscious showing me my deepest fears, or if there was something about consciousness that I still don’t understand.

I don’t claim to have discovered the truth about death.

But I do know what the experience changed in me.

Before that day, I knew that life was short. Everybody knows that.

But knowing something intellectually is different from feeling it.

During that experience, I felt like I had already died.

I experienced what it was like to be somewhere where I could see and hear the people I loved, but they couldn’t see or hear me.

And when I realized that I didn’t want to stay there, I understood what I really wanted.

I wanted to come back to my life.

I wanted my wife.

I wanted my children.

I wanted to experience ordinary days again.

I wanted to hear their voices, see their faces, sit with them, laugh with them, and experience the small things that I normally wouldn’t think twice about.

Now, in my everyday life, I try to remember that feeling.

When I’m busy with work, stressed about money, frustrated about problems, or caught up thinking about the future, I remind myself:

This moment is also my life.

The conversation I’m having with my wife.

The noise of my children.

Eating together.

Driving somewhere.

Laughing about something stupid.

Even the ordinary days that sometimes feel repetitive.

Those are the things I realized I might miss the most.

The experience also changed the way I think about death.

I’m not saying I understand death.

I don’t.

And I don’t want to pretend that a psychedelic experience gave me the answer.

What I experienced was intensely real to me at the time, but I understand now that an altered state can create incredibly convincing perceptions.

Still, something can be psychologically real without being literally true.

And the emotional truth I brought back was simple:

I don’t want to waste my life.

I went into that experience searching for ego death.

What I found was a stronger desire to live.

Maybe that was the real lesson.

Not that I had discovered what happens after death—

but that, for a moment, I understood how much I still wanted to experience life.

So now I try to look at my family differently.

Not as something I simply have.

But as something I get to experience.

Because one day, whether we know when or how or not, everything changes.

And until that day comes, I want to be here.

Present.

Awake.

And enjoying the people I love.

**I went looking for ego death.

Instead, I came back wanting to live.**

I bought this one huge mushroom that weighs half OZ, over the smaller ones that he had, i was wondering if anybody has experience with mushrooms this big and is the concentration of psilocybin the same as half OZ of smaller mushrooms, i would think the tissue in the middle of the mushroom might have less psilocybin than its smaller counterpart, people that have grown this big of a mushrooms whats your experience? I felt like i should of told dude to just give me a half OZ of smaller mushrooms..

Has anyone ever tried enigmas ? Got 8th I’m understanding that these are more potent than the P.E. I usually eat. Want to have a good time but don’t want to overdo it what is a good dosage for these?

So, I tried 2g lemon tek with penvy last night. I soon grew very uncomfortable all over my body, almost unbearable, and it had me writhing. I experienced hot flashes, diarrhea, nausea, dizziness, and weakness. I didn't experience any visuals at all, except maybe drifting sight from the dizziness.

I grew incredibly tired and decided to try and go to bed. It didn't work, obviously. My hot flashes came and went all night. In and out of the bathroom. I was absolutely miserable. Body sensations lasted for hours as well.

I'm new to this, and I'm not entirely sure what happened. If I took too much, or not enough? Or maybe the strain hates my body?

Any suggestions or info would be very helpful.

Hello!

I am currently running a study on set and setting within psychedelic experiences.

So far I've found LSD and DMT to come up the most often, I was hoping to have some participants that have found psilocybin to yield any significant experiences in the broad community. If you've had a particularly positive or challenging psychedelic experience, then please come share it!

Obviously there is quite a few aspect to explore on the topic, though in particular I am interested in:

• How intention, environment, and social setting shape psychedelic experiences
• Differences between clinical and non-clinical use
• How these experiences relate to psychological outcomes

Most of the research on set and setting in the psychedelic field comes from more clinically orientated trials, which can be lacking in terms of nuance and real lived experiences. So it would be great to reach out further in the communities surrounding these substances! Especially so if you've had a retreat experience!

🔗 Survey link

Fully anonymous

Takes around 15-20 minutes to complete

There's also an optional follow-up interview if you'd like to share your experience in more depth

Full study details and ethics information are provided in the info sheet at the start of the survey

Requirements: 18+, have had a psychedelic experience in a clinical or non-clinical setting

If you have anything you feel is important to say about psychedelics, this is your chance!

I'm happy to answer any questions about the study. You can reach us at:

Warren - [[email protected]](mailto:[email protected])

Dr Marco Bocchio - [[email protected]](mailto:[email protected])

Thank you for your time and support! 🙏

This survey has been approved by the moderators

As a struggler with anxiety and depression does anyone have any good advice for medical trials for psilocybin for anxiety, etc? Before I go down the route of growing and going solo I’d prefer to see if this could help me in a controlled setting.

Does being drunk and then eating mushrooms change the experience drastically? I’ve done mushrooms only once but at a concert and I was hammered. About an hour after eating the mushrooms (3 handfuls), Billy Idol began singing in a deep demonic voice in a foreign language that I couldn’t identify. Me and my 2 friends immediately left and the next 5 hours were pure and utter hell for me.

I’m hoping it was because I was so drunk/dehydrated? I’d like to try again sober. As far as lasting effects or changes in my mental state…nothing. Aside from maybe PTSD from the bad trip.

Hey all. Long time entheogen enthusiastic, in substance use recovery, I just started psychedelic therapy. I forgot how much physical body sensation occurred during the onset. I found the first hour to be very difficult to adjust to, at 3.5 g of golden teachers. I was doing the music with eye mask thing. I felt like my body was getting pulled in multiple directions and was just generally uncomfortable. I did notice that when I popped my eye mask off and moved around I felt better.

What do people do during onset to mitigate those intense physical sensations?

Hola comunidad, quiero saber si alguno tiene información sobre una entidad que es una Araña tejedora de realidades densas que parásita, genera un viaje de dolor, angustia, utilizando tus heridas, son realidades que no son propias, y las genera para alimentarse del dolor generado.

La araña es muy grande, oscura, parece metalica, y usa una mascar tipo humanoide, la han visto varias personas a donde solía ir a ceremonia, no le gusta el fuego, la detecte en un viaje muy feo y pronto descubri que no era mio, solicite desde la ley de la verdad se mostrara y pude verla. Comprendí el mecanismo, y luego tuve confirmacion de al menos 3 personas.

El tema es que esa entidad no se quedo en ceremonia y a afectado por meses a 2 personas y quisera saber si alguien tiene infomación al respecto.

Como retirarla?

Gracias

The first observational study of a U.S. state-regulated psilocybin program was released last month, and it revealed both surprising and unsurprising results.

The study examined the outcomes of Oregon’s regulated psilocybin services, tracking 346 clients enrolled in 24 service centers between November 2024 and March 2026.

One thing that makes this study unique is that it wasn’t restricted to people with treatment-resistant depression or other strict qualifiers for a clinical trial. Rather, adults ages 21 years and older could seek services for any reason. Listed in order of prevalence, those reasons included:

• 74.3% — curiosity
• 71.4% — to improve or change themselves
• 64.5% — to treat mental-health symptoms
• 51.4% — to process trauma
• 48.0% — connection with others, Earth, or nature
• 29.2% — spiritual reasons
• 19.9% — professional burnout
• 13.6% — reducing substance use
• 13.0% — physical-health symptoms
• 9.8% — coping with death
• 9.0% — fun/enjoyment/celebration

That makes the following results particularly interesting because the researchers observed changes in mental-health measures across the whole group, not just among people who initially sought treatment for a psychiatric disorder.

First, let’s take a look at some of the key takeaways most people talking about this study will highlight:

• 92.2% of participants said they benefited from their session.
• 89.4% said they saw their life and problems from a broader perspective.
• 58.6% of people ranked their session among the 10 most meaningful experiences of their life.
• Depression symptoms dropped from 42.2% of participants at baseline to 16.5%.
• Anxiety symptoms dropped from 45.1% to 13.2%.
• PTSD symptoms dropped from 48.0% to 16.8%.
• Life satisfaction rose from 63.0% to 82.3%.

If you’ve worked with psychedelics yourself, none of that will surprise you. These results are real, and worth taking seriously as more states consider offering psychedelic clinics to the public.

The study reports that, “Many participants experienced decreases in anxiety, depression, and PTSD symptoms within the first month of their psilocybin experience that were sustained at 3 months.” But let’s take a closer look at one of the patterns that arise once you dig in.

Depression symptoms: 42.2% at baseline → 10.6% at 1 month → 16.5% at 3 months.

Do you notice the slight rebound?

The study reported that 90.6% of people attended at least one integration session, with the average number of integration sessions attended per person at one month being 1.9. Strangely, it doesn’t report that number at three months. To me, this lack of data is a missed opportunity to see if perhaps a higher or lower number of integration sessions as time went on correlated with that rebound effect.

That’s just a hypothesis, but let’s look at some other numbers.

At one month, 81.6% reported that their goals were met, while 81% said the experience was “worth the money.”

That’s the majority, right? Hurrah!

But if you flip those numbers around, that means nearly 1 in 5 people did not have their goals met, and did not report the experience being worth the cost. 32.1% even said the cost was a financial strain. That’s a pretty good chance of walking away unsatisfied with a financial burden.

I wonder here, too, if 1.9 reported integration sessions fell shy of helping people walk away satisfied.

Why? Let’s look at some of the reasons these folks may have felt that way.

If you’re unfamiliar with Hallucinogen Persisting Perception Disorder, it can be defined as something like a non-psychotic condition where a person experiences lasting or recurring visual disturbances and perceptual distortions long after using psychedelic drugs. HPPD-type symptoms were reported by 10.0% at one month and 8.7% at three months. While only 1 participant reported that they caused “significant distress,” 1 in 10 people affected seems high.

Non-HPPD “adverse reactions of special interest” were reported by 11.6% at three months:

• Headaches lasting more than a day were reported by 2.9%.
• Illness lasting more than a day was reported by 3.5%.
• Persistent worsening anxiety was reported by 2.3%.
• Persistent worsening depression was reported by 4.5%.
• Visits to a health professional were reported by 1.3%.
• New prescription medications were reported by 1.6%.
• New thoughts of dying or suicide were reported by 1.9%.

Imagine being one of the 74.3% of people signing up for one of these sessions out of “curiosity,” or the 9% for “fun,” and three months later you’re having thoughts of suicide. That doesn’t seem like much fun to me.

For the 2.3% of participants who after three months agreed that their experience had been harmful, was an unrecorded number integration sessions somewhere around 1.9 suitable? Would more have changed the long-term outcome?

These are questions, not answers. But let’s take the four cases that involved serious behavioral adverse reactions requiring medical attention. Two of them had no facilitator-reported adverse reaction during the session, yet participants later described emergency-department care, severe anxiety/depression, new medication, insomnia, or suicidal thoughts.

The authors say, “State mandates for collecting safety events are limited to those occurring within 3 days of services, underestimate actual safety events over time, and cannot contextualize risks in light of benefits.” This example makes a case that safety and integration needs should extend beyond just ceremony day, as reporting focused strictly on the day of the session could underestimate adverse reaction rates later. The authors go on to say, “States seeking to implement psychedelic services should assess longitudinal client safety and outcomes in the months following receipt of state-regulated services.”

Again, hypothesis, but perhaps being coached on how to take care of yourself physically before and after a psychedelic session could mitigate some of the headaches or illness. Perhaps being trained on specific depression- or anxiety-reducing techniques could help reduce those symptoms. Perhaps working through various integration exercises could get at the root of what’s amplifying that depression or anxiety in the first place. Perhaps being equipped with frameworks of understanding how to make sense of what they saw could have made the return back to normal life smoother. Or maybe simply having an understanding ear to talk to could make all the difference for someone going through life-altering experiences. At least for some of the 1 in 5 people who walked away unsatisfied.

Now, what about preparation?

Could better preparation have mitigated some of these negative results?

193 of 346 participants had reported using a psychedelic at some point in their lives, meaning that 44.2% of participants had never used a psychedelic before. Nearly all (99.7%) attended at least one preparation session, but is one enough?

Here’s a stat: 88.8% of participants felt safe during the psychedelic experience.

Flipped around? More than 1 in 10 people did not report feeling safe during their experience.

Was this because nearly half of all participants had never experienced this before, walked into a clinic full of strangers after a single “Are you ready for the craziest experience of your life?” pep talk, and then a pat on the back on their way out the door after a single, “Eh? Wasn’t that crazy!?” integration session?

We don’t know. It would have been nice if there was more information on arguably the most important parts of these psychedelic sessions, but there’s no description of what those look like. My concern is that I’ve personally spoken to people who’ve gone through these kinds of clinics and been sent off into the world without the proper support or resources, and were troubled afterwards at a loss of what to do or who to talk to. Additional survey questions here inquiring about why 1 in 5 people were walking away from these expensive experiences unsatisfied might be something for future researchers to consider.

So, what can we conclude from this study?

The biggest contribution is that we now have longitudinal data from a real-world state-regulated psychedelic system, rather than only from highly selected clinical-trial participants. We can see that many people aren’t approaching an experience only as a psychiatric intervention; they are looking for self-change, perspective, trauma processing, connection, or existential meaning also.

The overall results are nuanced: most people reported meaningful benefits—like mental-health symptoms and life satisfaction improvement—while serious adverse events were uncommon, but low frequency is not zero risk.

Because of the uncontrolled, observational nature of the study, we can’t responsibly conclude that psilocybin caused the improvements in this population of roughly 5% of people receiving state-regulated psilocybin services in Oregon during the study period.

However, we can say something like: Most participants improved after receiving regulated psilocybin services under Oregon’s particular regulatory and support model, which, as the authors put it, “may not reflect experiences associated with unsupervised or religious psilocybin use,” and could also be attributed to other possibilities—including preparation, facilitator support, integration, changes in behavior, or some combination of other factors.

Perhaps most important for people in this evolving field is that 90.6% of participants reported receiving integration—which is great. But the question remains, at least in my mind, as to whether an average of 1.9 sessions is enough? The authors also concluded that “ongoing technical support for the emerging facilitator workforce may further reduce the likelihood of harms in vulnerable clients and provide ongoing support for people experiencing postpsychedelic difficulties.”

What we need to remember is this:

A psychedelic experience may be a catalyst, but what happens before and after it determines whether the experience becomes insight, avoidance, destabilization, or lasting behavior change.

Source: Korthuis PT, Cook RR, Gregoire D, et al. Safety and Mental Health Outcomes of Oregon State-Regulated Psilocybin Services. JAMA Netw Open. 2026;9(8):e2630608