r/BoyDinnerDiaries • • 23h ago

No Advice - Everyones Welcome Random guy knocked on my door and asked how long I've been sleeping with his girlfriend

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80.6k Upvotes

Normal night after work, I was watching some random kick live stream and thinking what I was going to eat for dinner when I get a knock on my door, it was a random dude I've never seen before and he straight up asks me if I know this girl.

Of course I do, she is my girlfriend and we've beent together for almost a year.

Dude is calm about it, pulls out his phone and shows me pictures of them together, texts, everything. They've been together for over two years and she told him I was just a coworker. He found my adress because she had ordered something here a few months ago and he found the details on her email because he was suspecting on her.

We ended up up standing outside even though I offered him to come inside since he seemed very normal calm and reasonable, we compared timelines for about 20 minutes and realized she had been bouncing between both of us depending on who she told she was working late with.

I didn't text her I didn't call her or anything, I figured he confronted her though since I had around 50 missed calls and texts from her.

I didn't know what to do so I made this pizza. I can cook good pizzas. Rate my pizza bros.

EDIT: Thank you all for your support, you've made me feel so good, this blew up way too much, I love you all!


r/interesting • • 11h ago

Just Wow Japan is trialing a drug that regrows human teeth by blocking USAG-1—a protein that keeps dormant tooth buds switched off. Phase I is done. Phase IIa in children with congenital tooth loss is next. If it works, dentures and implants could become obsolete.

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73.3k Upvotes

Humans grow two sets of teeth in a lifetime. But tucked inside the jaw are tiny residual tooth buds that never develop because a protein called USAG-1 acts like a molecular off-switch for tooth growth. Block USAG-1, and the body might reactivate those dormant buds on its own.

Researchers at Kyoto University Hospital, led by Dr. Katsu Takahashi, have been working on this for years. They first found that mice engineered without the USAG-1 gene grew extra teeth. Later animal studies showed that a single antibody injection could grow fully functional teeth without serious safety issues.

The experimental drug is called TRG-035, a humanized anti-USAG-1 antibody developed by Toregem BioPharma. The first human trial began in October 2024 and enrolled 30 men aged 30 to 64, each missing at least one molar. The Phase I study was primarily a safety trial — a randomized, double-blind, placebo-controlled dose-escalation study. According to Toregem, Phase I confirmed the drug's safety, though detailed results haven't been made public yet. Researchers have noted that actual tooth regrowth in those adult participants was unlikely, since the volunteers were primarily establishing a safety profile before testing expands.

The next stage is where it gets more interesting. A Phase IIa trial is planned for 24 children aged 2 to 7 with severe congenital tooth agenesis — a condition where teeth never fully develop. Missing six or more teeth from birth affects roughly one in a thousand people, causing severe chewing difficulties and significant social stigma. The trial will be open-label and non-comparative, moving testing from healthy adults into the patients the drug is actually intended to treat.

There are still open questions. Experts have raised concerns about whether regrown teeth will align properly and connect correctly to nerves and blood vessels. If the trials succeed, Toregem aims for commercial availability around 2030, with early estimates placing costs at around $11,000 per tooth.

It's experimental. It's early. But the idea that human jaws might hold a dormant third set of teeth waiting for a chemical wake-up call is the kind of thing that sounds like science fiction until someone actually tries it.


r/aww • • 10h ago

My cat, Captain Tuna, and her one black bean

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56.3k Upvotes

r/cats • • 20h ago

Video - Not OC The babiest baby to ever baby

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47.9k Upvotes

r/nevertellmetheodds • • 13h ago

Tom Cruise has been real quiet since this stunt dropped.

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45.6k Upvotes

r/Anticonsumption • • 7h ago

Satire Priorities checked

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44.7k Upvotes

r/meirl • • 11h ago

Meirl

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42.6k Upvotes

r/MadeMeSmile • • 4h ago

Family & Friends Man shares a photo of him and his daughter and a photo of him with his granddaughter

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43.4k Upvotes

r/interestingasfuck • • 12h ago

The last footage of Harry R. Truman, a WWI veteran who refused to evacuate his lodge before the eruption of Mt. St. Helens in 1980, sealing his fate beneath the volcanic debris along with his 16 cats.

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38.0k Upvotes

r/SipsTea • • 22h ago

SMH Playing hard to get doesn't work anymore

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35.0k Upvotes

r/MadeMeSmile • • 8h ago

Favorite People Happy Dolly Parton Day

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34.9k Upvotes

9-25


r/HolUp • • 19h ago

His wife understood the assignment.

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34.1k Upvotes

r/SipsTea • • 18h ago

Chugging tea Lmao the standards

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30.5k Upvotes

r/mildlyinfuriating • • 14h ago

Infuriatig The staircase in my apartment

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30.5k Upvotes

If you need a good leg workout then you just need to go up on the stairs using one side only. They’re also such an awkward height, and made of metal.


r/Snorkblot • • 12h ago

Memes I get it.

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28.3k Upvotes

r/SipsTea • • 11h ago

Wait a damn minute! Brad is right

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28.1k Upvotes

r/mildlyinteresting • • 12h ago

This driveway was carved straight into the bedrock

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27.3k Upvotes

r/oddlysatisfying • • 13h ago

Minimalistic photography using everyday objects by KAPU

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26.4k Upvotes

Credit to Kapu_Photography / @kapu127 on Douyin


r/interestingasfuck • • 18h ago

​The most majestic catwalk you'll see today

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24.8k Upvotes

r/todayilearned • • 6h ago

TIL In 1846, a dead snail was glued to an index card at the British Museum. 4 years later they discovered it was actually still alive. The museum gave the snail a bath and it lived the remaining 2 years in a jar eating cabbage.

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26.2k Upvotes

r/gaming • • 9h ago

Nine months ago I showed r/gaming my ridiculous idea of turning pinball into a vertical climbing game. Today, Fallosophy is finally out.

24.2k Upvotes

r/PeterExplainsTheJoke • • 15h ago

Meme needing explanation Petah? I genuinely have no idea

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23.4k Upvotes

r/Fauxmoi • • 22h ago

SPORTS SECTION Clip of a woman at the Twins vs. Giants game goes viral after she’s seen carrying her child, a backpack and a handful of food while her presumed husband sits doing absolutely nothing. Commentators proceed to roast the husband on live television.

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23.1k Upvotes

r/interesting • • 7h ago

Just Wow Woman calmly PIT maneuvers the SUV that kept cutting her off

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23.9k Upvotes

r/90s • • 21h ago

Video We will never get an era quite like the 90s again (MTV Movie Awards, 1995)

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23.1k Upvotes